Selective brain damage modulates human spirituality, research reveals

New research provides fascinating insight into brain changes that might underlie alterations in spiritual and religious attitudes. The study, published by Cell Press in the February 11 issue of the journal Neuron, explores the neural basis of spirituality by studying patients before and after surgery to remove a brain tumor.

Although it is well established that all behaviors and experiences, spiritual or otherwise, must originate in the brain, true empirical exploration of the neural underpinnings of spirituality has been challenging. However, recent advances in neuroscience have started to make the complex mental processes associated with religion and spirituality more accessible.

"Neuroimaging studies have linked activity within a large network in the brain that connects the frontal, parietal, and temporal cortexes with spiritual experiences, but information on the causative link between such a network and spirituality is lacking," explains lead study author, Dr. Cosimo Urgesi from the University of Udine in Italy.

Dr. Urgesi and colleagues were interested in making a direct link between brain activity and spirituality. They focused specifically on the personality trait called self-transcendence (ST), which is thought to be a measure of spiritual feeling, thinking, and behaviors in humans. ST reflects a decreased sense of self and an ability to identify one's self as an integral part of the universe as a whole.

... "If a stable personality trait like ST can undergo fast changes as a consequence of brain lesions, it would indicate that at least some personality dimensions may be modified by influencing neural activity in specific areas," suggests Dr. Salvatore M. Aglioti from Sapienza University of Rome. "Perhaps novel approaches aimed at modulating neural activity might ultimately pave the way to new treatments of personality disorders."

The researchers include Cosimo Urgesi, Universita` di Udine, Udine, Italy, Istituto di Ricovero e Cura a Carattere Scientifico Eugenio Medea, Pordenone, Italy; Salvatore M. Aglioti, Sapienza Universita` di Roma, Roma, Italy, Istituto di Ricovero e Cura a Carattere Scientifico Fondazione S. Lucia, Roma, Italy; Miran Skrap, Azienda Ospedaliero-Universitaria Santa Maria della Misericordia, Udine, Italy; and Franco Fabbro, Universita` di Udine, Udine, Italy, Istituto di Ricovero e Cura a Carattere Scientifico Eugenio Medea, Pordenone, Italy.

via Selective brain damage modulates human spirituality, research reveals.