Monday, July 19, 2010

Vaccine patch may replace needles

Close up of microneedles on a the vaccine patchThe tiny microneedles are loaded with vaccine

A vaccine patch could cut out the need for painful needles and boost the effectiveness of immunisation against diseases like flu, say US researchers.The patch has hundreds of microscopic needles which dissolve into the skin.Tests in mice show the technology may even produce a better immune response than a conventional jab.Writing in Nature Medicine, the team of researchers said the patch could one day enable people to vaccinate themselves.Each patch, developed by researchers at Emory University and the Georgia Institute of Technology, contains 100 "microneedles" which are just 0.65mm in length.Related stories Fridge-free vaccine hopes raised New slow-release vaccine heraldedThey are designed to penetrate the outer layers of skin, dissolving on contact.To test the technology, the researchers loaded the needles with an influenza vaccine.One group of mice received the influenza vaccine using traditional hypodermic needles and another group were vaccinated with the patch.Patches that had no vaccine on them were applied to a third group of mice.Three months down the line the team found the patch appeared to produce a more effective immune response in mice, then infected with the flu virus, than a standard vaccination. ...

via BBC News - Vaccine patch may replace needles.

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